Global incidence of early-onset cancer increasedby 79.1% (1990-2019)
A very interesting study published by the British Medical Journal cites a 79% increase in early onset-cancer from 1990 to 2019. This is a remarkable increase and should be global news! Our hope in helping our customers understand their health is an ability to benchmark to the world stage. This study is a great example of how the world is doing. Sadly, it isn't the best news and we all need to start taking better care of ourselves with a healthy diet and supplement regime, exercise, minimize tobacco and alcohol, and and the end of the day, "moderation is the best strategy" when it comes to those ever pressing devils in our lives :). Please take a look and we hope you enjoy this quarter's update!
Objective This study aimed to explore the global burden of early-onset cancer based on the Global Burden of Disease (GBD) 2019 study for 29 cancers worldwid.
Methods and analysis Incidence, deaths, disability- adjusted life years (DALYs) and risk factors for 29 early- onset cancer groups were obtained from GBD.
Results Global incidence of early-onset cancer increased by 79.1% and the number of early-onset cancer deaths increased by 27.7% between 1990 and 2019. Early- onset breast, tracheal, bronchus and lung, stomach and colorectal cancers showed the highest mortality and DALYs in 2019.
Globally, the incidence rates of early-onset nasopharyngeal and prostate cancer showed the fastest increasing trend, whereas early-onset liver cancer showed the sharpest decrease. Early-onset colorectal cancers had high DALYs within the top five ranking for both men and women. High-middle and middle Sociodemographic Index (SDI) regions had the highest burden of early-onset cancer. The morbidity of early-onset cancer increased with the SDI, and the mortality rate decreased considerably when SDI increased from 0.7 to 1. The projections indicated that the global number of incidence and deaths of early- onset cancer would increase by 31% and 21% in 2030, respectively. Dietary risk factors (diet high in red meat, low in fruits, high in sodium and low in milk, etc), alcohol consumption and tobacco use are the main risk factors underlying early-onset cancers.
Conclusion Early-onset cancer morbidity continues to increase worldwide with notable variances in mortality and DALYs between areas, countries, sex and cancer types.
Encouraging a healthy lifestyle could reduce early-onset cancer disease burden.
Zhao J, Xu L, Sun J, et al. Global trends in incidence, death, burden and risk factors of early-onset cancer from 1990 to 2019. BMJ Oncology