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Maitake Mushroom, Fucoidan, + Vitamin C enhance cancer cell death and prevention

October 16, 2017

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Seaweed Extract, Fucoidan, found to help inhibit Prostate Cancer and Female related cancers - New Research Suggests

 

As shown in past key articles regarding the unique seaweed extract, fucoidan, new research is further validating fucoidan's anti-cancer properties.  

 

In one study, researchers showed that Fucoidan may be a promising cancer preventative medicine due to its inhibitory effects and induction of human prostate cancer cells.  They used a common cancer cell line, DU-145.  Fucoidan significantly decreased viability of DU-145 cancer cells in a concentration-dependent manner as shown by MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay. The compound also significantly increased chromatin condensation, which indicates apoptosis (cell death), in a concentration-dependent manner.(1) 

 

In another study, researchers reviewed fucoidan and it's anti-estrogenic modes of action and assessed other potentially biologically relevant anti-tumor effects in estrogen receptor (ER)-dependent and independent female cancer cell lines.  Amazingly, in the seaweed species, fucus vesiculosus, via and its fucoidan content, showed an induction of autophagy and apoptosis (cell death) on breast, endometrial and ovarian cancer cell lines suggesting additional anti-tumor actions that are independent of ER status in female cancers.(2)

 

Truly impressive results using fucoidan and the same species that we have used in our integrative medicine product portfolio!  

 

References

 

1.  Gang-Sik Choo, et. al.  Anticancer Effect of Fucoidan on DU-145 Prostate Cancer Cells through Inhibition of PI3K/Akt and MAPK Pathway Expression. Marine Drugs.  7 July 2016

 

2. Zhang et al. BMC Complementary and Alternative Medicine (2016) 16:151 DOI 10.1186/s12906-016-1129-6

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